Acne and eczema

Acne and eczema

This collection contains only supplements relevant to supporting skin conditions such as acne, eczema, or combination skin inflammation. Both acne vulgaris and atopic or seborrheic dermatitis can be related to internal factors such as gut dysbiosis, immune activation, hormonal imbalance, or oxidative stress.
This collection focuses specifically on supplements that directly or indirectly influence these underlying factors.

Important pathways of action in this collection:

Gut-skin axis and microbiota

• Lactobacillus rhamnosus GG
  The most studied probiotic strain for eczema and allergies. It can reduce immune activation via IL-10 induction.
• Bifidobacterium lactis HN019
  Supports the barrier function of the intestinal mucosa, relevant in eczema with intestinal leakage.
• Saccharomyces boulardii
  Non-pathogenic yeast, helps balance the microbial environment and reduce pro-inflammatory toxins.

Hormonal regulation (especially for acne)

• DIM (Diindolylmethane)
  Cruciferous vegetable extract supports healthy estrogen metabolism. May affect hormone-related acne.
• Zinc
  Regulates the conversion of testosterone to DHT and influences sebum production.
• Vitex agnus-castus
  A herbal remedy that can influence luteinizing hormone. It is primarily used for female hormonal acne.

Anti-inflammatory and barrier function

• Omega-3 (EPA/DHA)
  Modulation of inflammatory pathways via resolvins and prostaglandins. Clinically proven in skin inflammation.
• Vitamin D3
  Regulates T-cell activity and strengthens the skin's barrier function. Deficiency is common in eczema.
• Quercetin
  Flavonoid that reduces mast cell activity and inhibits histamine release, relevant for itching and allergic components.
• Vitamin A (retinyl palmitate or retinyl acetate)
  Essential for keratinization and sebum regulation. A standard treatment for severe acne.

Liver and elimination support

• Choline
  Necessary for fat metabolism in the liver, indirectly supports hormone balance.
• Milk thistle (silymarin)
  Influences liver detoxification and antioxidant protection, with potential impact on skin conditions.
• N-Acetylcysteine (NAC)
  Precursor of glutathione, has antioxidant and mucolytic properties, sometimes effective in inflammation-related acne.

Cofactors and barrier-supporting nutrients

• Vitamin C
  Essential for collagen synthesis, supports the recovery of skin structure.
• Biotin (B8)
  Classically used for dry skin or seborrheic eczema.
• Zinc
  Not only hormone regulating, but also essential for wound healing and inflammation control.
• Selenium
  Antioxidant and cofactor for glutathione peroxidase. Used for chronic skin conditions with oxidative stress.